Marc E Rothenberg Selected Research

Chemokine CCL24

7/2010	IL-13 induces esophageal remodeling and gene expression by an eosinophil-independent, IL-13R alpha 2-inhibited pathway.
11/2008	Intestinal macrophage/epithelial cell-derived CCL11/eotaxin-1 mediates eosinophil recruitment and function in pediatric ulcerative colitis.
10/2006	A central regulatory role for eosinophils and the eotaxin/CCR3 axis in chronic experimental allergic airway inflammation.
10/2005	The eotaxin chemokines and CCR3 are fundamental regulators of allergen-induced pulmonary eosinophilia.
4/2005	Identification of a cooperative mechanism involving interleukin-13 and eotaxin-2 in experimental allergic lung inflammation.
11/2003	Eotaxin-2 and IL-5 cooperate in the lung to regulate IL-13 production and airway eosinophilia and hyperreactivity.

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Marc E Rothenberg Research Topics

Disease

77	Eosinophilic Esophagitis 03/2023 - 03/2002
68	Inflammation (Inflammations) 03/2024 - 02/2003
58	Eosinophilia 01/2023 - 02/2002
42	Asthma (Bronchial Asthma) 12/2023 - 06/2002
24	Hypersensitivity (Allergy) 01/2023 - 06/2002
13	Hypereosinophilic Syndrome (Loeffler Endocarditis) 01/2022 - 01/2004
11	Hyperplasia 01/2016 - 11/2003
10	Gastrointestinal Diseases (Functional Gastrointestinal Disorders) 01/2023 - 06/2002
9	Atopic Dermatitis (Atopic Eczema) 01/2024 - 07/2006
8	Food Hypersensitivity (Food Allergy) 12/2017 - 04/2008
8	Mastocytosis 01/2016 - 12/2003
7	Fibrosis (Cirrhosis) 12/2018 - 09/2006
6	Deglutition Disorders (Dysphagia) 11/2023 - 06/2015
6	Neoplasms (Cancer) 01/2022 - 07/2002
6	Infections 01/2021 - 01/2005
6	Esophagitis 01/2017 - 11/2006
5	Eosinophilic enteropathy 01/2023 - 01/2020
5	COVID-19 01/2022 - 01/2020
5	Anaphylaxis (Anaphylactic Shock) 10/2015 - 03/2005
5	Respiratory Hypersensitivity 04/2011 - 04/2005
5	Pneumonia (Pneumonitis) 05/2007 - 10/2004
4	Diarrhea 04/2016 - 12/2003
4	Gastroesophageal Reflux (GERD) 05/2015 - 11/2006
4	Pulmonary Eosinophilia (Eosinophilic Pneumonia) 09/2008 - 11/2003
3	Allergic Rhinitis 01/2023 - 07/2006
3	Lung Diseases (Lung Disease) 01/2020 - 11/2003
3	Disease Susceptibility (Diathesis) 01/2018 - 02/2006
3	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 05/2011 - 11/2008
3	Insulin Resistance 02/2009 - 07/2006
3	Metaplasia 12/2006 - 09/2006
2	Cardiomegaly (Heart Hypertrophy) 12/2018 - 05/2006
2	Obesity 01/2017 - 04/2010
2	Hypertrophy 10/2015 - 12/2006
2	Parasitic Diseases (Parasitic Disease) 08/2014 - 05/2012
2	Systemic Mastocytosis 01/2014 - 09/2008

Drug/Important Bio-Agent (IBA)

46	AllergensIBA 03/2024 - 03/2002
41	Interleukin-13IBA 01/2024 - 06/2002
31	CytokinesIBA 12/2023 - 06/2002
26	Interleukin-5 (Interleukin 5)IBA 01/2022 - 02/2002
22	AntigensIBA 01/2023 - 02/2003
15	Interleukin-4 (Interleukin 4)IBA 12/2022 - 06/2003
14	ChemokinesIBA 10/2015 - 02/2003
13	Immunoglobulin E (IgE)IBA 01/2020 - 02/2003
12	Biomarkers (Surrogate Marker)IBA 01/2022 - 11/2006
12	Chemokine CCL11IBA 03/2016 - 11/2003
12	OvalbuminIBA 09/2015 - 10/2003
11	Proton Pump InhibitorsIBA 11/2023 - 06/2012
11	Proteins (Proteins, Gene)FDA Link 01/2023 - 05/2005
11	Chemokine CCL26IBA 05/2015 - 02/2006
10	Messenger RNA (mRNA)IBA 01/2022 - 06/2003
8	RNA (Ribonucleic Acid)IBA 01/2022 - 12/2013
8	MicroRNAs (MicroRNA)IBA 12/2018 - 04/2009
8	CollagenIBA 07/2010 - 10/2004
7	dupilumabIBA 11/2023 - 01/2020
7	GlucocorticoidsIBA 01/2023 - 12/2007
7	mepolizumabIBA 01/2022 - 01/2004
7	ArginaseIBA 05/2012 - 06/2003
6	Interleukin-33IBA 10/2021 - 02/2013
6	Chemokine CCL24IBA 07/2010 - 11/2003
5	Peptide Hydrolases (Proteases)FDA Link 01/2023 - 04/2016
5	Monoclonal AntibodiesIBA 01/2023 - 03/2008
5	AcidsIBA 12/2022 - 01/2012
5	ResistinIBA 09/2015 - 07/2006
5	Chemotactic FactorsIBA 10/2009 - 02/2003
4	Thymic Stromal LymphopoietinIBA 12/2023 - 07/2010
4	Interleukin-4 Receptors (Interleukin 4 Receptor)IBA 01/2023 - 03/2005
4	SteroidsIBA 01/2023 - 02/2007
4	Interleukin-5 Receptors (Interleukin 5 Receptor)IBA 01/2023 - 11/2013
4	Serine Proteases (Serine Protease)IBA 10/2021 - 10/2020
4	InterleukinsIBA 05/2016 - 06/2002
4	Fluticasone (Cutivate)FDA LinkGeneric 08/2014 - 07/2004
4	Arginine (L-Arginine)FDA Link 06/2010 - 10/2004
3	cendakimabIBA 01/2023 - 01/2019
3	Anti-Bacterial Agents (Antibiotics)IBA 01/2022 - 01/2018
3	CalpainIBA 01/2018 - 04/2016
3	Interleukin-9 (Interleukin 9)IBA 10/2015 - 04/2008
3	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 01/2014 - 05/2006
3	Interleukin-17 (Interleukin 17)IBA 02/2013 - 03/2006
3	Interleukin-12 (IL 12)IBA 09/2011 - 04/2009
3	Immunoglobulins (Immunoglobulin)IBA 08/2010 - 09/2005
3	STAT6 Transcription FactorIBA 05/2007 - 02/2003
3	Histamine (Histamine Dihydrochloride)FDA Link 03/2005 - 02/2003
2	Amino Acids FDA Link 01/2023 - 12/2022
2	benralizumabIBA 01/2023 - 01/2022
2	reslizumabIBA 01/2022 - 02/2012
2	anti-IgE antibodiesIBA 01/2022 - 12/2003
2	VaccinesIBA 01/2022 - 08/2003
2	Ac-GQFR-kbtIBA 10/2021 - 05/2021
2	SerpinsIBA 01/2021 - 10/2020
2	LigandsIBA 01/2019 - 10/2005
2	Tryptases (Tryptase)IBA 12/2016 - 07/2010
2	AntibodiesIBA 04/2016 - 03/2005
2	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 10/2015 - 02/2013
2	Neutralizing AntibodiesIBA 02/2012 - 08/2006
2	Cytokine Receptors (Cytokine Receptor)IBA 03/2011 - 10/2006
2	Immunoglobulin G (IgG)IBA 12/2010 - 03/2005

Therapy/Procedure

33	Therapeutics 01/2023 - 01/2004
2	Immunotherapy 01/2022 - 02/2003
2	Precision Medicine 01/2022 - 01/2018
2	Ambulatory Care (Outpatient Care) 01/2022 - 01/2022